Best Soccer Bets This Week: Soccer Betting Picks for 18-22 August
Updated 16 Jul, 2026
Editorial Review By: Henrik Norman
Senior Sports & Casino Editor
Mid-August means the return of top-flight European soccer, and the weekend of August 21-22 marks the official kickoff for both the Premier League and Serie A. This opening weekend is notoriously tricky for oddsmakers, creating early value opportunities before the market adjusts to new managerial systems and summer transfers.
In England, the Friday night lights return to the Emirates as Arsenal hosts newly promoted Coventry City, while Saturday sees Manchester United travel to MKM Stadium to face Hull City. Over in Italy, the Serie A campaign kicks off with a Saturday slate featuring Inter Milan beginning their title defense at San Siro against Monza, and Napoli taking on Genoa. Check back on game day as our models finalize the best moneyline, spread, and totals projections for the opening weekend.
