Tuesday’s Big East rivalry between Seton Hall and St. John’s carries major implications for conference positioning and bragging rights. The Seton Hall Pirates arrive looking to rebound from back‑to‑back defeats, including an ugly home loss to Butler in their most recent outing. The St. John’s Red Storm have been firing on all cylinders of late, riding a four‑game win streak into this showdown at Madison Square Garden in New York. Before this contest begins at MSG, continue reading to get my Seton Hall vs St. John's prediction on the court.
Our Seton Hall vs St. John’s Pick
Pick:
St. John's -9.5 ATS PRO
Confidence:
3/5
Game Snapshot
Matchup: Seton Hall Pirates @ St. John’s Red Storm
Date & Time: Tuesday, January 20, 2026, 7:00 PM ET
Venue: Madison Square Garden, New York, NY
Broadcast: FS1
Key Storylines
St. John’s has won four straight games heading into this clash, including impressive wins over Creighton, Marquette, and Villanova. They shoot a high field goal percentage and have multiple scoring options, led by Zuby Ejiofor and Bryce Hopkins during the streak. Ejiofor leads the Red Storm in points, rebounds, and assists this season and he will be a key factor in this contest as well.
Seton Hall has struggled recently with perimeter shooting, going 10‑of‑54 from three over their last four outings and struggling to find consistent scoring. No Seton Hall player averages 12 points per game or more this season, as the Pirates prefer to win games on the defensive end of the floor.
The Red Storm will enjoy the crowd advantage at MSG and have leaned on efficient transition offense and strong second‑half performances to pull away from opponents. It will be interesting to see if Seton Hall can bring some crowd support to this game as well, as they are located in nearby New Jersey. St. John's could see its usual home-court advantage at MSG dulled somewhat against a local rival.
The clash of styles in this game will be interesting. St. John's averages over 10 points per game more than Seton Hall, while Seton Hall allows 9.1 points per game less than the Red Storm. The tempo of this game could go a long way in determining the outcome.
Head‑to‑Head & Betting Trends
St. John's is 65-50 all-time against Seton Hall.
The Johnnies have won three straight games over the Pirates.
Seton Hall is 11-7 against the spread going into this matchup.
St. John's is 10-6-1 against the spread entering Tuesday night.
The under is 10-8 in Seton Hall's games this year.
The under is 10-7 in St. John's games this year.
Seton Hall vs St. John’s Model Projection
Score Projection: Seton Hall 68 – St. John’s 83 ATS PRO
Win Probability: Seton Hall 27%, St. John’s 73% ATS PRO
Final Thoughts
This Big East rivalry tilt favors St. John’s in most analytical categories. Their offensive efficiency, depth, and confidence from stringing quality wins together all suggest they will control the flow of this game and cover the spread. Look for the Red Storm to win by double-digits at home and for them to get a fifth straight victory here.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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