St. John’s rides a 7-game winning streak into Chicago with a chance to keep climbing the Big East standings against DePaul. DePaul looks to steady the course after a two-game road losing streak against Georgetown and Xavier. The Red Storm have rediscovered their edge with a bigger lineup, defending and rebounding at a high level, and pushing the tempo into the mid-80s on the scoreboard. DePaul has been feisty at Wintrust Arena, leaning on guard shot creation and a frontline that can carve out second chances. Here, I break down this Big East game and give you my St. John's vs DePaul prediction in college hoops.
Our St. John’s vs DePaul Pick
Pick: St. John’s -10.5 ATS PRO
Confidence: 3/5
Game Snapshot
Matchup: St. John’s Red Storm @ DePaul Blue Demons
Date & Time: Tuesday, February 3, 8:00 PM ET
Venue: Wintrust Arena, Chicago, Illinois
Broadcast: Peacock
Key Storylines
Form guide: St. John’s enters 16-5 overall and 9-1 in Big East play after a 92-70 win over Butler, improving to a 7-game win streak. DePaul sits 12-10 and 4-7 in the conference after a 70-61 loss at Georgetown that they followed up with a 68-66 loss at Xavier.
Top scorers: St. John’s senior center Zuby Ejiofor leads the team at 15.7 points and 7.4 rebounds per game with 2.0 blocks. DePaul’s CJ Gunn paces the Blue Demons at 14.5 points, while NJ Benson grabs 7.0 boards and Layden Blocker dishes out 3.6 assists per game.
Tempo and shot profile: St. John’s averages 85.4 points on 47% shooting with 16.2 assists, thriving in early offense and attacking the rim. DePaul averages 72.4 points per game on 45% shooting, with more reliance on half-court creation.
Rim protection and boards: The Red Storm blocks 5.0 shots and pulls down 38.6 rebounds per game, driving their recent defensive improvement. DePaul sits at 33.5 boards with 3.7 blocks per game, making keeping St. John’s off the glass a priority.
Standings update: The Red Storm enter this game at 9-1 in conference play, trailing UConn by one game in the loss column going into this matchup. UConn is a heavy favorite tonight against Xavier and St. John's can't afford to lose with that in mind.
Head-to-Head & Betting Trends
Past meeting: St. John’s beat DePaul 79-66 on December 16, 2025 in Queens.
ATS and O/U records: St. John’s is 11-8-1 ATS overall this season. DePaul is 15-6-1 ATS this season. Totals trends show St. John’s 9-11 to the Under and DePaul 7-15 to the Under.
Home and road splits: St. John’s is 5-0 away from home. DePaul is 9-3 at Wintrust this season.
St. John’s vs DePaul Model Projection
Score Projection: St. John’s 78 – DePaul 66
Win Probability: St. John’s 74%, DePaul 26%
Final Thoughts
St. John’s checks more boxes than DePaul: elite recent form, road consistency, and the size/athleticism blend that can shrink DePaul’s driving lanes and erase second chances. The Blue Demons’ best path is a whistle-friendly game that gets them to the stripe and turns this into a slow grinder, but St. John’s depth and rim control should protect against that outcome. I recommend laying the points with St. John's in Big East action on Tuesday night.
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