The Washington Huskies will take on the USC Trojans on Saturday as the Huskies head to Los Angeles hoping to pull off an upset. Washington (5‑3, 0‑1 Big Ten) is coming off a close 82‑80 loss to the UCLA Bruins in their Big Ten opener. On the other side, USC (8‑0, 1‑0 Big Ten) remains unbeaten, and is coming off a resilient 82‑77 win over the Oregon Ducks. Here, I've broken down this Big Ten contest and you can find my Washington vs USC prediction below.
Our Washington vs USC Pick
- Pick: USC -6.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Washington Huskies @ USC Trojans
- Date & Time: Saturday, December 6, 2025, 6:00 PM ET
- Venue: Galen Center, Los Angeles, California
- Broadcast: Big Ten Network
Key Storylines
- USC remains unbeaten at 8‑0 and has started conference play with a win. Their pace and scoring output has been impressive, as they are averaging 90.6 points per game. Their ability to pile up points is especially dangerous against teams that struggle defensively.
- Washington showed guts in their loss to UCLA. Steinbach’s 29‑point night, along with solid contributions from perimeter shooters like Zoom Diallo and Wesley Yates III, suggests UW can score in bursts. The hope is they can translate that into consistency on offense.
- For USC, a wildcard remains Rodney Rice. He’s averaged 20.3 points per game, but he’s been sidelined for the last two contests with a shoulder issue and is listed as day-to-day. If he’s limited, the burden will shift even more heavily to other scorers like Chad Baker-Mazara, who has been strong, averaging over 20 points per night.
- Defensively, Washington has to be better if they want to contend with teams in the Big Ten. The Huskies have allowed 80 or more points in two straight games, losses to Colorado and UCLA. They will have their hands full on the defensive end of the floor here as well against a potent USC squad.
Head-to-Head & Betting Trends
- USC has dominated recent meetings with Washington. They won their last matchup in March 2025 by 31 points (92‑61), and they also claimed a decisive 85‑61 road win in December 2024.
- USC is 5-3 against the spread so far this season.
- Washington is 4-4 against the spread going into this matchup.
- USC has gone over the total in 5 of their first 8 games this year.
- The Huskies are 3-4-1 in the over/under market heading into this contest.
Washington vs USC Model Projection
Score Projection: Washington 75 – USC 83
Win Probability: Washington 30%, USC 70%
Final Thoughts
USC’s offense, even without Rodney Rice, is simply too deep and efficient for Washington to keep pace with. The Huskies have struggled on the defensive end, which has given them too much of a burden to shoulder on offense. With home‑court advantage at the Galen Center and strong recent form, USC looks like the safer bet to cover the spread and I will lay the points with the Trojans.
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