The Chicago Cubs and Los Angeles Dodgers continue their weekend series on Saturday at Dodger Stadium. Chicago enters riding a 10-game winning streak after a dramatic comeback victory in the opener, while Los Angeles looks to regroup and even the series with a win here. With both teams sitting near the top of the standings at 17-9, this Cubs vs Dodgers matchup is one of the most significant in MLB on Saturday.
Cubs vs Dodgers Pick
Pick: Chicago Cubs ML
Confidence: 3 out of 5
Game Snapshot
Matchup: Chicago Cubs vs Los Angeles Dodgers
Date & Time: Saturday, April 25, 2026, 7:15 PM
Starting Pitchers: Colin Rea vs Roki Sasaki
Stadium: Dodger Stadium, Los Angeles, CA
Broadcast: FOX
Key Storylines
The Chicago Cubs have won 10 straight games, including a 6-4 comeback win in Game 1.
Los Angeles has dropped 3 of its last 4 games and has not scored more than 4 runs in any of those games.
Chicago's offense has scored 5 runs or more in each of the team's last 5 games, which has been a huge reason for their winning streak.
Games like this could have an impact on who gets home-field advantage in the National League later in the season, given how good both of these teams have been early on.
Pitching Matchup
Colin Rea enters at 3-0 with a 3.00 ERA and 1.04 WHIP.
Roki Sasaki is 0-2 with a 6.11 ERA and 1.87 WHIP.
Rea has allowed just 2 home runs and 5 walks in 24 innings.
Sasaki has issued 12 walks in 17.2 innings, signaling control concerns.
Key Players
Dansby Swanson delivered a clutch home run in the series opener and will be a dangerous weapon for the Cubs in this contest.
Nico Hoerner leads the Cubs with 23 RBI and a .299 average.
Andy Pages is hitting .333 with 21 RBI for the Dodgers.
Shohei Ohtani has 5 home runs and remains a central offensive threat.
Max Muncy leads LA with 8 home runs early in the year.
The over hit in the first game between these teams, with 10 total runs scored.
The Cubs are 16-9-1 to the over so far this year.
The under is 14-12 in Dodgers games this season.
Cubs vs Dodgers Model Projection
Score Projection: Chicago Cubs 5 - Los Angeles Dodgers 4
Win Probability: Chicago Cubs 52%, Los Angeles Dodgers 48%
My projections make this another close game, with Chicago holding a slight edge due to current form and pitching reliability. Colin Rea has been efficient, limiting base runners and keeping the ball in the park, which is critical against a Dodgers lineup that thrives on power. On the other side, Roki Sasaki has struggled with command, and facing a Cubs lineup that is producing runs late in games could create pressure early if he falls behind in counts.
With the combination of pitching form and recent team trends supporting my projections, backing the Cubs to win as an underdog in this game is a decent value for me. I'll go with Chicago to take a second straight in LA and an 11th straight overall.
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