Memphis Grizzlies vs Cleveland Cavaliers Prediction - 11/15/2025
Updated July 9, 2026
The Cleveland Cavaliers host the Memphis Grizzlies on Saturday in a game that is expected to be one-sided. Cleveland enters with a winning record and is looking to shake off their recent struggles against a Grizzlies team that is in the midst of a losing streak. Not sure what to bet in this matchup in the NBA? Find out who I like below as I make my Grizzlies vs Cavaliers prediction.
Pick: Cavaliers -10.5
Confidence: ★★★★☆
Player | Prop |
|---|---|
Donovan Mitchell | Over 28.5 Points |
Jaren Jackson Jr. | Under 5.5 Rebounds |
Score Projection: Cavaliers 122 – Grizzlies 110
Win Probability: Cavaliers 65%, Grizzlies 35%
The Grizzlies have made a habit of losing games by double-digits lately. I expect that trend to continue in this game on the road against a very good Cavaliers team. Look for Cleveland to improve to 5-2 on their home floor for the season with a win that would drop Memphis to 1-5 on the road. I'll lay the points with Cleveland in this one.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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