The Philadelphia 76ers travel to Indianapolis on Tuesday to face the Indiana Pacers in a game between two Eastern Conference teams having very different years. The 76ers have stayed competitive in the Eastern Conference, while the Pacers sit near the bottom of the league standings. As is always he case when these teams are involved, injury and availability concerns for both sides will help determine the outcome of this one. You can find my 76ers vs Pacers prediction below.
Our 76ers vs Pacers Pick
Pick: Pacers +8.5 ATS PRO
Confidence: 2 out of 5
Game Snapshot
Matchup: Philadelphia 76ers @ Indiana Pacers
Date & Time: Tuesday, February 24, 2026, 7:00 p.m. ET
Venue: Gainbridge Fieldhouse, Indianapolis, IN
Broadcast: NBA League Pass
Key Storylines
The 76ers enter this game with a much better overall record and have two wins in two meetings against Indiana this season. Philadelphia’s offense has been productive, and Tyrese Maxey has been one of the league’s top scorers.
The Pacers are struggling without key pieces. Star guard Tyrese Haliburton remains sidelined with a torn Achilles and has also dealt with illness, limiting Indiana’s offensive ceiling. Pascal Siakam is questionable to compete in this game with a wrist injury.
It wouldn't be a Philadelphia 76ers game without injury concerns. Joel Embiid is questionable with a shin ailment, while Paul George is still serving a drug ban.
Key Players
Philadelphia 76ers
Tyrese Maxey – Maxey has paced the 76ers in scoring this season, averaging about 29.0 points per game while also contributing strong assist numbers. His ability to break down defenders off the dribble and score at all three levels makes him the focal point of the offense. In games where Maxey eclipses 25 points, Philadelphia’s winning percentage jumps significantly.
Andre Drummond – Drummond provides interior strength and rebounding, averaging roughly 8.8 boards per game. His work on the glass creates second-chance opportunities and limits opponents’ possessions. Against a Pacers team that has struggled defensively inside, Drummond’s physical presence could tilt the rebounding battle.
V.J. Edgecombe – The rookie forward has supplied scoring and perimeter spacing this year. His ability to knock down open shots keeps defenses honest and opens driving lanes for Maxey and the rest of the backcourt.
Indiana Pacers
Pascal Siakam – Siakam leads Indiana with 23.9 points per game and remains the most reliable offensive option. He can score in isolation, attack in transition, and stretch the floor. If the Pacers are going to keep this game close, Siakam likely needs to produce 25 or more points.
Andrew Nembhard – Nembhard averages around 7.5 assists per game and has taken on greater playmaking responsibility. With Haliburton out, Nembhard’s decision-making and ability to control tempo are essential for keeping turnovers down. He is also questionable for Indiana here.
Jay Huff – Huff offers rim protection and energy in the paint. His shot blocking and ability to alter attempts help compensate for Indiana’s defensive shortcomings.
Stat Comparison
Stat
76ers
Pacers
Points per game
116.2
111.5
Points allowed per game
116.0
119.0
Team Field Goal %
45.8%
45.0%
Rebounds Per Game
43.3
42.7
Assists Per Game
24.6
26.3
Head-to-Head & Betting Trends
The 76ers have won both prior meetings this season and have averaged 114.0 points per game against Indiana.
Indiana is 28-30 against the spread this season.
Philly enters this contest with a 31-26 record against the spread for the season.
76ers vs Pacers Model Projection
Score Projection: 76ers 117 – Pacers 112 ATS PRO
Win Probability: 76ers 75%, Pacers 25% ATS PRO
Final Thoughts
It is very difficult to feel confident in either of these teams going into this matchup, given that two of the best players in this game are questionable for their respective teams. Still, I'd take the points with the Pacers in this matchup, as they have been respectable during the second half of the season and should keep this game close against a Sixers team that relies far too heavily on Maxey for scoring.
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