Florida Gators vs Ole Miss Rebels Prediction - 11/15/2025
Updated July 9, 2026
The Florida Gators (3‑6) and Ole Miss Rebels (9‑1) will battle in SEC play on Saturday night in Oxford. Ole Miss comes into this game with just one loss on the season and with their College Football Playoff hopes still alive. Florida is reeling and searching for answers late in the regular season. Here, I break down this contest from SEC country and give you my Florida vs Ole Miss prediction.
Pick: Ole Miss -11.5
Confidence: ★★★★☆
Ole Miss enters this game as a true national title contender. They enter this week with a 9‑1 record and ranked seventh in the latest College Football Playoff rankings. They beat up on The Citadel of the FCS last week and should be relatively fresh going into this important matchup against a conference opponent.
Florida is trying to salvage what has been a difficult season. They are 3-6 and they need to win out to qualify for bowl season. The Gators’ interim leadership has yet to steady the ship, and their offense has been held to 13.5 points per game over the last two games. Florida has dropped three of its last four games and they need to figure out how to get their offense going to have any chance of upsetting the Rebels here.
Ole Miss quarterback Trinidad Chambliss has emerged as a dual‑threat weapon in the SEC. Through 10 games, he’s passed for 2,356 yards, 13 touchdowns, and only 2 interceptions. He's also rushed for 434 yards and 6 touchdowns. Florida quarterback DJ Lagway has thrown for 1,762 yards, 11 touchdowns, and 12 interceptions so far this season. His QBR is in the 50s and his turnover rate is problematic. Ole Miss has a huge edge in the quarterbacking department and will try to use that to their advantage to get a win in this one.
Score Projection: Ole Miss 35 – Florida 14
Win Probability: Ole Miss 88%, Florida 12%
Ole Miss is clearly the superior team in every major metric going into this game. Florida’s season has been disappointing and they will continue to struggle here as they go on the road against a top-tier opponent. I'm going to lay the points with Ole Miss in this game, as they should be able to generate enough offense to create separation against a dismal Gators squad.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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