The Missouri Tigers will travel to Jordan-Hare Stadium to take on the Auburn Tigers in SEC play on Saturday night. Missouri comes into this game as a slight favorite on the road and will look to prove that they belong among the SEC's elite by passing this road test. Auburn is still searching for its first SEC win of the 2025 season. Before kickoff from SEC country, continue reading to get my Missouri vs Auburn prediction.
Our Missouri vs Auburn Pick
- Pick: Missouri -1.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Missouri Tigers vs Auburn Tigers
- Date & Time: Saturday, October 18, 2025, 7:45 PM ET
- Venue: Jordan-Hare Stadium, Auburn, AL
- Broadcast: SEC Network
Key Storylines
- Missouri's Road Performance: Missouri has struggled in true road games, with a 6-15 record under coach Eli Drinkwitz. This game marks their first away game of the season after six straight home games. Overcoming this challenge is crucial for any postseason aspirations they may have.
- Auburn's Defensive Strength: Auburn boasts one of the nation's top defenses, ranking 11th in the country in run defense. Their ability to stop the run will be tested against Missouri's potent ground attack.
- Quarterback Play: Missouri's Beau Pribula has thrown 11 touchdown passes this season and played well in last week's loss to Alabama. His performance will be key in exploiting Auburn's defense. Auburn's Jackson Arnold has just five touchdown passes through Auburn's first six games. His struggles have prevented the Auburn offense from getting going during SEC play thus far.
- SEC Implications: Missouri enters this game at 1-1 in the SEC and they are in desperate need of a win to avoid falling too far behind the leaders in the conference standings. Auburn is 0-3 in the SEC and has been held to 12.3 points per game against conference opponents so far.
Betting Trends
- Missouri's Recent Performance: Missouri has a 3-2-1 record against the spread this season.
- Auburn's Struggles Against the Spread: Auburn has a 2-3-1 record against the spread this season. They have had a hard time keeping up with their competition in the SEC so far.
- Over/Under Trends: The over/under for this game is set at 43.5 points. Missouri's games have gone over the total in five of their six games this season. Auburn's games have gone under the total five times in six outings.
Missouri vs Auburn Model Projection
- Score Projection: Missouri 24 – Auburn 20
- Win Probability: Missouri 55%, Auburn 45%
Final Thoughts
This will be a big test for the Missouri Tigers. They have to go on the road for the first time this season and prove that they can get the job done in a hostile environment. But I was encouraged by their performance against Alabama last week. I think that Mizzou will prove that they are the best Tigers in the SEC by winning on the road against Auburn and dropping Auburn to 0-4 in the SEC.
Jay Sanin
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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