Oklahoma Sooners vs Alabama Crimson Tide Prediction - 11/15/2025


The Alabama Crimson Tide and Oklahoma Sooners will meet in a Saturday afternoon game that carries significant College Football Playoff implications. Alabama (8-1) hosts Oklahoma (7-2) at Bryant Denny Stadium in Tuscaloosa with the Crimson Tide ranked fourth in the country and on an eight-game winning streak. The Sooners are ranked 11th and need a victory to keep their playoff hopes alive. Before kickoff in the SEC, you can find my Oklahoma vs Alabama prediction below.
Ty Simpson of Alabama is the key to his team's success. His 67% completion rate, 21 touchdowns, and just one interception reflect his outstanding efficiency and decision-making. Against a top-tier Oklahoma defense, his poise will be tested.
John Mateer’s dual-threat abilities give the Sooners flexibility on offense. But his passing numbers have fallen off since he got hurt. He is clearly a great competitor but he will need to execute at the highest level if the Sooners are going to pull off an upset in this game.
Score Projection: Alabama 24 – Oklahoma 17
Win Probability: Alabama 60%, Oklahoma 40%
The Oklahoma defense should make life difficult on the Alabama offense going into this game. But I still think that the Crimson Tide have the upper hand in this matchup. Mateer will fail to match the output of Ty Simpson, who will make a Heisman Trophy level statement as the Tide should win and cover the number on Saturday.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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