Oklahoma State vs Texas Tech Pick & Prediction - 10/25/2025


The Oklahoma State Cowboys (1–6, 0–4 Big 12) will travel to Lubbock to face the Texas Tech Red Raiders (6–1, 3–1 Big 12) on Saturday. With the Cowboys struggling to find their footing this season, and the Red Raiders aiming to bounce back after a loss, the Red Raiders are heavy favorites at home in this contest. Before kickoff in this Big 12 matchup, continue reading to get my Oklahoma State vs Texas Tech prediction.
Oklahoma State has faced significant challenges at the quarterback position. Redshirt freshman Zane Flores has struggled, while senior Sam Jackson V has transitioned from wide receiver to quarterback. He brings athleticism but has struggled with his production. Texas Tech's Will Hammond has demonstrated poise and capability, even in the loss to Arizona State.
I think we are going to see a blowout between Oklahoma State and Texas Tech on Saturday afternoon. The Cowboys have been one of the worst teams in all of FBS football this season, not just among power conference teams. Their struggles will continue against a potent Texas Tech offense that is hungry to bounce back after their first loss of the season.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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