The Indiana Pacers (0-1) will face the Memphis Grizzlies (1-1) on Saturday night at FedExForum in Memphis. The Pacers come into this game with an 0-1 record after losing in double overtime in an NBA Finals rematch. They will try to even their record against a Grizzlies team that is 1-1 to start the year. Before tip-off in this NBA matchup, continue reading to get my Pacers vs Grizzlies prediction.
Our Pacers vs Grizzlies Pick
- Pick: Indiana Pacers Moneyline
- Confidence: 3/5
Game Snapshot
- Matchup: Indiana Pacers @ Memphis Grizzlies
- Date & Time: Saturday, October 25, 2025, 8:00 PM ET
- Venue: FedExForum, Memphis, TN
- Broadcast: NBA League Pass
Key Storylines
- Pacers' Injury Woes: The Pacers are dealing with multiple injuries, including the absence of star guard Tyrese Haliburton due to an Achilles injury. Rookie Kam Jones faces legal issues following an arrest. Guards TJ McConnell and Andrew Nembhard are also out.
- Grizzlies' Injury Concerns: Memphis is also facing injury challenges. Ja Morant is listed as week-to-week due to an ankle sprain. Other key players like Brandon Clarke and Zach Edey are also dealing with injuries, impacting the team's depth.
- Offensive Adjustments: Both teams are adjusting to key player absences, which may affect their offensive efficiency and overall ability to perform.
- Rest Advantage: Memphis played last night, getting blown out by the Miami Heat. They will try to bounce back here but will need to overcome any fatigue from playing on the second night of a back-to-back. Indiana played two overtimes in their last game, but that was on Thursday and they should be fine to play at a high level here.
Head-to-Head & Betting Trends
- Recent Matchups: The Pacers and Grizzlies split their two meetings last season, with both teams winning once. This is their first meeting of the 2025-26 season.
- Against the Spread (ATS): The Pacers covered the spread in their season opener against OKC. Memphis is 1-1 against the spread going into this contest.
- Over/Under (O/U): The over is 1-0 in Pacers games this season and 2-0 in Grizzlies games.
Best Player Props to Watch
Player | Prop |
|---|
Pascal Siakam (Pacers) | Over 22.5 Points |
Jaren Jackson Jr. (Grizzlies) | Over 8.5 Rebounds |
Ja Morant (Grizzlies) | Under 7.5 Assists |
Pacers vs Grizzlies Model Projection
- Score Projection: Pacers 123 – Grizzlies 118
- Win Probability: Pacers 52%, Grizzlies 48%
Final Thoughts
If you like defensive basketball, this might not be the game for you. Both of these teams are going to try and push pace and put up huge numbers on the scoreboard. I think that the Pacers will ultimately win this game, as they are the fresher team and better equipped to make the offensive plays needed down the stretch to get the win here.
Jay Sanin
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
Affiliate Disclosure
ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
