Philadelphia 76ers vs Chicago Bulls Prediction - 11/4/2025
Updated July 9, 2026
The Philadelphia 76ers and Chicago Bulls will meet in a huge Eastern Conference matchup in the NBA on Tuesday night. Both of these teams have identical 5-1 records and have been very impressive early on. But only one of them can come away with a win in Chicago here. Before tip-off from United Center, you can find my 76ers vs Bulls prediction below.
Both squads are off to 5-1 starts despite major injury concerns. The Bulls are 4-0 at home and looking to lean into their advantage at United Center. The 76ers arrive in Chicago on a three-game road win streak to start the season. Something has to give in this matchup in terms of those unbeaten starts at home and on the road.
Injuries will continue to impact these teams going into this game. Chicago will be missing Zach Collins and Coby White, with Ayo Dosunmu listed as questionable. The Sixers' big absence is Paul George, while we could see Jared McCain suit up for Philadelphia after he missed some time to begin the year.
Philadelphia's guard duo of Tyrese Maxey (33.7 PPG, 9.0 APG) and V.J. Edgecombe (20.3 PPG) have carried a heavy load for Philly given all of the uncertainty for them to start this season. The Bulls have enjoyed a very nice start from Josh Giddey (22.2 PPG, 8.7 APG). But both teams have received contributions from role players, who could make the difference again in this game.
Player | Prop |
|---|---|
Tyrese Maxey | Over 27.5 points |
V.J. Edgecombe | Under 16.5 points |
Josh Giddey (Bulls) | Over 21.5 points |
Score Projection: 76ers 125 – Bulls 129
Win Probability: Philadelphia 44%, Chicago 56%
Instead of betting against either of these red-hot teams, my best bet for this game is for the over to cash. The total is sky-high for this game, but that is justified given how effective both teams have been on offense to start the year. I'll bank on both teams to light up the scoreboard in what could be the best game of the night in the NBA.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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