Liberty vs Old Dominion Pick & Prediction - 9/27/2025


Liberty will travel to Norfolk this Saturday to take on Old Dominion in a non-conference college football matchup. The Flames enter at 1–3, trying to end a three-game losing streak. The Monarchs are 2–1 after a statement win over Virginia Tech. The spread heavily favors the home side, but can Liberty offer any resistance? Here, I break down this contest and give you my Liberty vs Old Dominion prediction for Saturday's game.
Spread | Moneyline | Total |
|---|---|---|
ODU –15.5 | ODU –750 / Liberty +475 | 53.5 |
Old Dominion's Colton Joseph has been a dual threat for his team. In the win over Virginia Tech, he passed for 276 yards and two touchdowns. He also added a rushing score, helping ODU pile up over 500 total yards. He leads the Monarchs in both passing yards and rushing yards this year.
Liberty’s offense has been more modest. Their passing game struggles to generate explosive plays, and turnovers have been a concern. Quarterback Ethan Vasko has averaged under 200 passing yards per game through four games. The Flames need to generate more through the air to win a game like this one.
ATS trends: ODU is 3–0 ATS so far this season. Liberty is 0–4 ATS.
Home/Road splits: ODU is 1-0 at home so far this season. They beat FCS NC Central 54-6 in their only home game of the season. Liberty is 0-2 on the road, losing by double-digits to Jacksonville State and Bowling Green away from home.
Over/Under tendencies: The total has gone over in two of ODU’s first three games. Liberty’s games have gone under their totals three times in four games.
Score Projection: Liberty 17 – ODU 38
Win Probability: Liberty 14%, ODU 86%
I am expecting another lopsided victory for Old Dominion against Liberty this weekend. The Monarchs are delivering on both sides of the ball and even kept things respectable against the explosive Indiana Hoosiers. I'll lay the points with Old Dominion as they should improve to 3-1 before getting into Sun Belt Conference play.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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