Chicago Bulls vs Detroit Pistons Prediction - 11/12/2025


The Chicago Bulls and Detroit Pistons will meet in an important Central Division contest in the NBA on Wednesday night. Detroit enters this game with the best record in the Eastern Conference and will try to keep their winning ways going against a Bulls team that has lost three games in a row. Before tip-off from Detroit, you can find my Bulls vs Pistons prediction below.
Pick: Chicago Bulls +2.5
Confidence: 2/5
Player | Prop Suggestion |
|---|---|
Cade Cunningham | Under 10.5 assists (if he plays) |
Nikola Vucevic | Under 10.5 rebounds |
Ayo Dosunmu | Over 1.5 made threes |
Score Projection: Detroit 118 – Chicago 116
Win Probability: Detroit 56%, Chicago 44%
I think we are in for a very close game between these Central Division rivals on Wednesday night. I would encourage bettors to wait to find out who is and is not going to be playing on both sides before locking any action in on this game. But with the injury reports being what they are now, I will take the points with Chicago, acknowledging that the line could move further in their favor if Cade Cunningham isn't able to go.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
Affiliate Disclosure
ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.